Journal of Liver Cancer

Jaejun Shim

2 Articles

A Case of Hepatocellular Carcinoma Presenting Early Intrahepatic Recurrence Following Hepatic Resection: Jaejun Shim, Byung-Ho Kim, Young Hwangbo, Sang Wook Lee, Young Ju Lee, Seung Hyung Ha, Jae Young Jang, Seok Ho Dong, Hyo Jong Kim, Young Woon Chang, Rin Chang, Sang Mok Lee; Journal of the Korean Liver Cancer Study Group. 2009;9(1):33-36. Published online June 30, 2009

Abstract PDF: Long term results of hepatic resection for hepatocellular carcinoma (HCC) are not satisfactory due to a high incidence of postoperative recurrence. To improve the prognosis in patients who underwent hepatic resection, identification of risk factors for recurrence and development of effective preventive strategies are required. A single nodular mass was found in the right hepatic lobe of 53-year old male with B viral cirrhosis by surveillance ultrasonography. Dynamic abdominal CT showed a 3 cm-sized hypervascular mass in the right posteroinferior segment (S6). AFP was 359 ng/mL. Child-Pugh classification was A, and ICG R15 was 18.8%. After preoperative transarterial chemoembolization (TACE), right hepatic wedge resection was performed. Resection margin was free of tumor. Microinvasions in the surrounding vessels, lymphatics, bile ducts were not found and microsatellite nodules were absent in the resected specimen. Although there were no risk factors that associated with high postoperative recurrence, multifocal intrahepatic recurrence in the right lobe and left medial lobe occurred at 7 months after hepatic resection. He underwent two sessions of TACE.

A Case of Advanced Hepatocellular Carcinoma Successfully Treated by Repeated Transcatheter Arterial Chemoembolization, Percutaneous Ethanol Injection and Surgical Resection: Jaejun Shim, Byung-Ho Kim, Jae Young Jang, Seok Ho Dong, Hyo Jong Kim, Young Woon Chang, Rin Chang, Sung Hwa Hong, Joo Hyeong Oh; Journal of the Korean Liver Cancer Study Group. 2008;8(1):120-123. Published online June 30, 2008

Abstract PDF: Here we report a case of multifocal advanced hapatocellular carcinoma successfully treated by repeated transc atheter arterial chemoembolization (TACE), percutaneous ethanol injection (PEI) and surgical resection. Previously healthy 54-year old man was admitted for the evaluation of incidental hepatic masses. Abdominal CT revealed multifocal hepatic masses in right lobe including segment 5, 6 and 8, which showed early wash-out pattern in portal phase and increased serum alpha fetoprotein (>840 ng/mL) was compatible with advanced hepatocelluar carcinoma (stage III). Underlying cirrhosis was noted and Child-Pugh classification was A (5 points). After 4 cycles of TACE, nodular masses in segment 6 and 8 were completely lipiodolized. Viable mass in the remained huge mass in right anterior lobe was treated by surgical resection. After 4 month operation, abdominal CT revealed new hepatoma lesion at right anterior lobe, serum AFP was increased to 61 ng/mL. The lesion was treated by one session of TACE. Underlying chonic hepatitis C was also treated with interferon and ribavirin. The patient has been followed for 9 years without evidence of regional tumor recurrence or distant metastasis.